Is your system truly inert? - A PREMIER experience
A PREMIER Opportunity to See What You’ve Been Missing!
Modern laboratories are challenged daily to meet business and scientific goals in a fast-changing environment. At Waters we understand that your data is critical in making important decisions that impact your lab. Meeting highest standards & ensuring confidence in your analytical results drive our innovations.
Newly introduced ACQUITY PREMIER Solutions are addressing the unwanted analyte/surface interactions that are at the root of many chromatographic challenges scientists still face today.
The ACQUITY PREMIER Solutions enable your lab to make informed decisions and reduce risk with stronger analytical capabilities to detect more of your sample components from the very beginning. Get the highest limits of detection, consistent results, and better recovery, so you can see what you couldn't before - all without time-consuming tasks like system passivation.
Whether working with peptides, glycans, or modified oligos, screening or quantifying small molecules, or discovering or validating biomarkers, you can:
- Increase confidence in your data
- Decrease time-to-result
- Reduce time on method development
- Increase overall efficiency in the lab
Is your system truly inert? - A PREMIER experience
Metal hardware has been used in chromatographic systems and columns since the advent of high-performance liquid chromatography, enabling low-cost manufacture and high-pressure capabilities. Stainless steel is commonly used in the construction of chromatographic columns and a variety of metal alloys, such as stainless steel, titanium and MP35N, are routinely used for chromatographic hardware.
A tradeoff of purposefully introducing metal surfaces in chromatographic systems is the introduction of electrostatic effects, electron sharing and Lewis acid-base interactions which leads to reduced analyte recovery and worsened peak shape. A large variety of analyte classes are impacted by these metal interactions, including small molecule metabolites, phospho-sugars, oligonucleotides, glycans and peptides.
The longstanding complication of adsorption of analytes with electron rich moieties has given rise to a variety of workarounds – reliance on chelating buffers and additives, sample derivatization techniques, system priming or passivation as well as utilization of non-metallic surfaces. The described approaches often sacrifice capabilities such as MS compatibility, high pressure capabilities or complicate workflows with multicomponent mobile phases or stringent system treatment protocols.
In order to address metal-based secondary interactions in LC and LC-MS analyses without the aforementioned performance compromises, we have developed the PREMIER Solution, which uses specialized inert LC surfaces to provide substantial improvements in sample recovery and peak shape.
Presenter: Amit Patel (Senior Scientist, Waters Corporation)
Amit is currently a Research and Development Senior Scientist in the Chemistry Organization at Waters Corporation. Amit’s scientific curiosity, collaborative spirit and passion for problem solving has led to the successful development and launch of liquid chromatography instruments, chromatographic columns, analytical standards and reagents. In the form of research dissemination and teaching on scientific principles, he has supported these technologies through application notes, research article, conference proceedings and direct engagements with chromatographers.
Currently, he is focused on the design and development of chromatographic columns to enable next-level performance. Smart connected products, automated method development and high throughput screening are some of his other R&D interests.
Presenter: Hélène Boiteux (Separations Product Marketing Manager, EMEA, Waters Corporation)
Hélène is a Product Marketing Manager in the European Marketing organization, responsible for Separation Technologies in Europe. Helping industrial and academic partners achieve their analytical goals, Hélène is keen to understand the current & future challenges & needs faced in the analytical laboratories, being the voice of our European customers for Liquid & Supercritical Fluid Chromatography product development & commercialisation. Before joining Waters, Hélène worked as a synthetic chemist in various pharmaceutical companies in the UK and France, then moved to sales specialist & product management roles for automated synthesis, compound management platforms, as well as SFC & Purification systems from other instrumentation companies. She holds a Chemical Engineering degree from Ecole Supérieure de Chimie Organique & Minérale in Cergy-Pontoise, France.
Presenter: Evelien Dejaegere (Marketing Manager Chemistry EMEA, Waters Corporation)
Evelien joined Waters in 2005 and is currently a Marketing Manager in the European Chemistry organization. She is passionate on leveraging products and solutions to solve analytical challenges "from sample to result" with the aim to help advancing science and basically make our world a better place.
Recently, Evelien has a focus on laboratory automation workflows, helping customers turn samples into results with robustness, reliability and reproducibility. Involved with product development and commercialisation, Evelien is keenly interested in learning about the challenges faced in the analytical laboratory, in order to facilitate the development of enabling technologies.
