Non-specific adsorption: Common causes, how it affects chromatographic results, and how to prevent it
Did you know, that non-specific adsorption (NSA) is a common cause of poor reproducibility, broad peak shapes and limited sensitivity? Have you ever had to include long column conditioning or passivation steps in your workflow to achieve your analytical results?
We will also introduce a new family of technologies and columns that were developed specifically to solve these challenges by reducing analyte/surface interactions to give chromatographers more control over their separations.
Key learning objectives:
- Learn how non-specific binding and adsorption impacts your analytical results
- Explore the techniques that can be used to overcome adsorption and binding losses
- Discover new technologies in columns and surfaces to reduce analyte loss due to uncontrolled binding
- See application examples across a wide range of analyte types
Who should attend?
- Scientists who struggle with long column conditioning and passivation times, poor reproducibility, sensitivity and peak shapes
- Chromatographers working with oligonucleotides, peptides, TCA cycle metabolites and other small molecules
- Analysts looking to ensure the best performance in their chromatographic separations by protecting against risk for reactive analytes without impacting other analytes
Presenter: Kim Haynes (Principal Product Marketing Manager, Waters)
Kim Haynes is currently a Principal Product Marketing Manager in the Chemistry Technology Center at Waters Corporation. Kim manages MaxPeak High Performance Surface Technologies as well as a variety of other programs. Prior to this position, she has worked with Waters Corporation as a chemistry sales specialist and a business development manager. During her 20 years at Waters, Kim has focused on helping customers and colleagues understand chromatographic separations and sample preparation. Before joining Waters Corporation, Kim worked as an analytical chemist at Bacardi Martini. She holds a BS in Chemistry from Ohio University. Kim can be contacted at [email protected]
Moderator: Sarah Thomas (Editorial Team, SelectScience)
Sarah studied biology at the University of Bath, UK, and has worked in the Pharmaceutical Sciences Department of St. Jude Children’s Research Hospital, Memphis. As a member of the Editorial team, Sarah plays an integral role in shaping the content on SelectScience.
