From Tires to Toxins: Optimizing your SPE & HPLC for EPA’s Draft Method 1634

EPA Method 1634 is a draft method introduced by the U.S. Environmental Protection Agency (EPA) to detect 6PPD-quinone (6PPD-Q) in water sources, particularly stormwater and surface water. 6PPD-Q, a by-product of 6PPD (a chemical additive in tires used to prevent rubber degradation), was linked to the mass deaths of salmon population streams in the Pacific Northwest. As vehicle tire particles break down, 6PPD interacts with ozone, forming the harmful 6PPD-Q compound, which subsequently washes into aquatic ecosystems through rainwater runoff.
The method uses liquid chromatography-tandem mass spectrometry (LC-MS/MS) for accurate 6PPD-Q measurement, providing customers with a crucial tool for monitoring water quality and protecting sensitive fish species and aquatic life. Although still in draft form, EPA Method 1634 supports ongoing research efforts aimed at understanding and mitigating the environmental impacts of 6PPD-Q contamination.
- Learn how to easily implement EPA Method 1634 draft, analysis of PPD-Q
- Achieve Method limit of 1 ng/L
- Learn Tips and Tricks for troubleshooting your assay.
