Mastering QC Oligonucleotide LC-MS in GMP Labs
Therapeutic synthetic oligonucleotides face unique analytical challenges in late-stage development. Meeting stringent regulatory requirements demands highly specific and sensitive methods like LC-MS. However, typical QC analysts struggle with the complexity of purity, assay and impurity profiling due to limitations in current chromatography and mass spectrometry data systems.
This webinar will explore a paradigm shift in software that streamlines the analytical workflow while maintaining data integrity and compliance. Our expert speakers will also discuss how to apply the Oligo Analysis Accelerator for OpenLabs CDS to your oligonucleotide therapeutic testing, helping you to optimize synthesis and purification.
Attend this webinar to:
- Discover how fit-for-purpose software for LC-MS analysis in QC lot release can save time and enhance quality
- Understand the fundamentals of ion-pair reversed phase LC-MS for oligonucleotides
- Discover how to use single quadrupole detector for impurity profiling of anti-sense oligonucleotides
Presenter: Charlotte Lekieffre, PhD (Biopharma Application Specialist, Agilent Technologies)
Charlotte holds a PhD from the Ecole Polytechnique Fédérale de Lausanne and has 10 years' experience in developing analytical workflows for mass spectrometry. She now brings her expertise to Agilent's customers as an LCMS Application Specialist in the BioPharma sector.
Presenter: Kevin Koelliker (Lab Informatics Application Engineer at Agilent Technologies)
Kevin is a Lab Informatics Application Engineer for Agilent Technologies. He studied Chemistry and Business informatics, and he worked as a Lab Technician, and as a Field Service Engineer before joining Agilent. Combined he has more than 15 Years of Experience in the analytical laboratory and therefore met already multiple different workflows. He works together with the Lab Informatics Product Specialists to demonstrate the Power of OpenLab, and to customize it to meet the needs of our Customers.
