Chemical Biology and Enzymology in Proteomics

Join CNPN and US HUPO's ECR as they explore innovative proteomic techniques aimed at studying PTMs, including proteolysis, and their profound impact on biological function.

Presenter: Chris Overall

Professor Chris Overall is a Distinguished University Scholar of the University of British Columbia, a fellow of the Royal Society of Canada, a Canada Research Chair Laureate in Protease Proteomics and Systems Biology, a Yonsei Distinguished Scholar of Yonsei University, Korea, and a Senior Fellow of the Freiburg Institute of Advanced Studies, AlbertLudwigs Universität Freiburg, Germany, where he is an Honorary Professor. His 310 papersare influential, with an h-index of 107. He is best known for his development of terminomic methodology for the identification of protein N and C-termini for the identification of mature and neo-protein substrate termini in vivo. He Chairs the HUPO Chromosome-centric Human Proteome Project (C-HPP), sits on the 1st Council of the pi-Hub Global Proteomics Project, and is the recipient of numerous awards, e.g., CNPN Tony Pawson Award, the Proteomass Scientific Society Award; 2018 HUPO Discovery Award in Proteomics Sciences; and 2022 Helmut Holzer Award.

Presenter: Amy Weeks

Amy Weeks is an Assistant Professor of Biochemistry at the University of Wisconsin-Madison. She received her S.B. in Chemistry from the Massachusetts Institute of Technology and earned her Ph.D. in Chemistry at the University of California, Berkeley under the mentorship of Prof. Michelle Chang. She completed postdoctoral studies in the laboratory of Prof. James Wells at the University of California, San Francisco. Her research group engineers enzymatic tools for mapping biological signals across space and time in living cells. Using these tools, the lab seeks to provide an integrated view of cellular signaling to advance biological discovery and development of therapeutics for human disease.