The Karl Fischer Oven Method – Step by Step
Three Webinars and a Roundtable with Experts from Merck KGaA, Darmstadt, Germany, Metrohm & Mettler Toledo
A Week Dedicated to Karl Fischer Titration!
Karl Fischer titration is still the most used, most accurate, and fastest method to determine water content in all kinds of sample matrices. This titration week covers different aspects that need to be considered when determining the water content in products, raw materials, and other substances. Experts from the life science business of Merck KGaA, Darmstadt, Germany, Metrohm AG, and Mettler Toledo will present and discuss different steps of the Karl Fischer titration process and how to improve it. Learnings include:
- Karl Fischer titration process and tips for how to improve it
- Karl Fischer oven method and its advantages
- Reference materials to use for titer determination, instrument check, and result verification
- Parameters needed to validate a Karl Fischer titration application
- News and future aspects of Karl Fischer titration
The Karl Fischer Oven Method – Step by Step
arl Fischer (KF) titration is a standard method for the water content determination in all types of substances. However, for various reasons, some substances are not suitable for a direct Karl Fischer titration. These reasons include that they undergo side reaction with KF reagents; they contaminate the titration cell and/or the electrodes; the substances are poorly soluble in alcohol; they release their water only slowly; or the water is released at high temperatures only. These problems can be avoided by using the oven method. This makes the KF oven method the perfect solution for the analysis of difficult samples. By attending this presentation, you will learn:
- The principle of the oven method
- How to properly prepare your titration system with an oven
- How to prepare your sample
- How to select the optimal oven temperature
After viewing this webinar, you will know how to perform accurate sample measurements using the oven method.
Presenter: Michael Margreth (Application Specialist - Karl Fischer Titration and Water Determination, Metrohm)
