Implementation of 2 - Dimensional Chromatography for Characterization of Non - Ionic Surfactants with Accurate Mass Time of Flight Spectrometry

In this talk, we will show characterization of ethoxylation in non - ionic surfactants. In the first dimension the separation is by degree of ethoxylation, while in the second dimension by the separation occurs by the length of the hydrophobic tail. This makes identification and quantitation possible in a single run.

Using Agilent 2D LC MassHunter 11 software coupled with the G6230A Accurate Mass Time of flight instrument. We have both quantitative and qualitative data. We can show ppb levels of quantitative detection with Personal Compound Database Library (PCDL) matching in a Walkup environment that a plant QC technician can use.

Presenter: Sue D'Antonio (Applications Scientist, Agilent Technologies, Inc.)

Sue D’Antonio joined Agilent (HP at that time) more than 30 years ago. For the last 15 years Sue has been an Applications Scientist in the Liquid Phase Separations Group. Sue’s application support extends to HPLC, UHPLC, CE and LCMS across a wide range of markets and customers.