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High-throughput and high-resolution N–glycan profiling workflows

ZÁZNAM | Proběhlo Út, 21.6.2022
V závodě o objevení dalšího slibného bioterapeutika nebo vyvinutí spolehlivého biosimilaru nelze slevit z analytické přesnosti a účinnosti.
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Agilent Technologies: High-throughput and high-resolution N–glycan profiling workflows
Agilent Technologies: High-throughput and high-resolution N–glycan profiling workflows

The location and structure of N-linked glycans play a critical role in the pharmacology of therapeutic proteins, potentially affecting immunogenicity, pharmacokinetics and pharmacodynamics. Glycosylation is considered one of the critical quality attributes of biomolecules. Therefore, there is a need to characterize, quantify, and determine if they are in acceptable ranges as part of the development process for a glycoprotein innovator, biosimilar, or bio-better pharmaceutical.

In the race to discover the next promising biotherapeutic or develop a reliable biosimilar, one cannot compromise on analytical accuracy and efficiency. Reducing process development time, having the ability to make procedural changes quickly, and minimizing variability in analyses are just a few of the challenges faced every day. Join us for a webinar to learn about these challenges and how to try and overcome them.

In this webinar, we will discuss about:
  • Preparation and analysis of released N-glycans from biotherapeutic glycoproteins
  • Achieve new levels of resolution for glycan mapping
  • Get next level of MS sensitivity
  • Reduce significantly the sample preparation time and boost N-glycan analysis productivity

Presenter: Dr. Rajni Mujoo (Technical Support Specialist, Chemistries & Supplies Division, Agilent Technologies)

Dr. Rajni is working with us as Technical Support Specialist in Chemistries and Supplies Division at Agilent Technologies since 2011. She has a Ph.D degree in Food Science from CFTRI, Mysore and Post Doctorate from Department Of Food Science, Michigan State University. She also has four International Presentations & 13 publications in reputed National & International journals to her credit. Rajni has a total work experience of 16 yrs spread across research and Sales building expertise in different Instrument techniques.

Agilent Technologies
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