Validating an expanded list of PFAS compounds from C4-C18 chain length
Exposure to manmade perfluoroalkyl and polyfluoroalkyl substances (PFAS) is of increasing concern due to their potential toxic effects and links to ecological damage and human health. These substances can be found in drinking, surface, waste and ground waters, but are also prevalent in food, household products, and even living organisms including fish and humans.
Recently, the state of California has expanded the required list of PFAS for analysis in wastewaters up to 42 PFAS compounds from C4 to C18 including carboxylic and sulfonic acids, sulfonamide derivatives, telomers, and ethers.
There are several methods for PFAS analysis, including ISO and EPA methods that are validated for a specific list of PFAS compounds using SDVB or WAX SPE for extraction and preconcentration prior to analysis by LC-MS/MS. However, the US Department of Defense (DOD) quality assurance manual suggests using a two-step SPE approach using WAX followed by a graphitized carbon black (GCB) cleanup.
In this webinar, David Schiessel, Babcock Labs, and Richard Jack, Phenomenex, will demonstrate the use of a dual, stacked WAX/GCB SPE method that uses a single step for C4-C18 PFAS compounds from waste-, surface- and groundwater extracts followed by LC-MS/MS.
Key learning objectives
- Find out more about the mission and work being performed by Babcock Laboratories for PFAS testing in water samples
- Method compliance using DoD QSM 5.3 standard for the expanded list of 42 PFAS compounds from the CA Resources Board from C4-C18
- Achieve robust and sensitive extraction and analysis using Strata-PFAS SPE followed by LC-MS/MS
Who should attend?
- Academic laboratories performing analytical chemistry research on emerging and existing environmental contaminants
- Country and state laboratories responsible for PFAS analysis
- Public water utilities or contract testing laboratories performing targeted PFAS testing
Presenter: Richard Jack (Global Market Development – Food and Environmental, Phenomenex Corporation)
Richard is the Global Market Development manager for the food and environmental markets with Phenomenex Corporation. His participation with the US EPA office of ground water and drinking water resulted in co-authoring EPA methods 557; 557.1 Richard is the second vice chair for the ASTM D19 water committee and drafted several ASTM methods including D4327 and D6919.
Richard received his M.S. in Ecology from the Univ. of TN, Knoxville, TN. and his Ph.D. in Biochemistry from VA Tech in Blacksburg, VA.
Presenter: David Schiessel (Organics Technical Manager, Babcock Labs)
David leads all research and development efforts at Babcock Labs for the analysis of organics using GC, LC, and IC coupled with tandem mass spectrometry. He has almost 20 years experience in the commercial environmental testing field and has brought numerous methods online.
His recent efforts have focused on a universal and scalable method for the targeted analysis of PFAS and has developed practical solutions for non-targeted analysis as well.
Presenter: Moderator: Finn Price (Editorial Team, SelectScience)
Fionnbhar Price is a member of the SelectScience Editorial Team, who plays a core role in sourcing and publishing content for the site, with a particular focus on the field of applied chemistry. He has an MChem in Chemistry from Cardiff University, UK, and undertook a year in research characterizing bacterial protein.
