Fast Analysis of Therapeutic Monoclonal Antibodies, Fragments, and Oxidation Variants Using a Super-Macro Porous Reversed-Phase Column Coupled with an Orbitrap Mass Spectrometer
Postery | 2015 | Thermo Fisher ScientificInstrumentace
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
ZaměřeníKlinická analýza
VýrobceThermo Fisher Scientific
Klíčová slovaoxidized, scfc, herceptin, mab, ides, mabfragments, figure, fragments, abundance, dtt, relative, papain, rapidseparation, mabpac, erml, rceptin, tic, fab, monoclonal, min, fragmentswere, scfcand, non, mmsodium, exactive, mass, orbitrap, plus, separated, andavastin, andf, digestionwas, faband, idesprotease, proteasewas, separationofofmab, separationthermostatted, thedigestion, heavychain, purchasedfrom, themab, time, carriedout, andmab, oxidizied, usingthermo, wereanalyzed, oxidation, ininthe, units
Podobná PDF
Characterization of Monoclonal Antibodies Oxidation Variants Using Middle-down Approach and Hydrogen/Deuterium Exchange Mass Spectrometry
2015|Thermo Fisher Scientific|Postery
There is a growing trend to obtain intact mass information as well as the glycan profile in the QC of mAbs using high resolution mass spectrometers. The most commonly employed LC/MS method is to desalt mAbs via reverse phase liquid…
Klíčová slova
trastuzumab, trastuzumabscfc, scfcoxidized, oxidizedmab, mabfigure, figureides, idesdeuterium, deuteriumfragments, fragmentsmabpac, mabpacoxidation, oxidationtic, ticfab, fabdtt, dttpapain, papainerml
Thermo Bio LC Columns - See your protein therapeutics in high resolution
2020|Thermo Fisher Scientific|Brožury a specifikace
See your protein therapeutics in high resolution Bio LC Columns Contents 2 Introduction to monoclonal antibody (mAb) characterization 3 Affinity titer determination 4 Aggregate separation 5 Charge variant analysis 6 Oxidation variant analysis 11 Antibody drug conjugates (ADCs) analysis 12…
Klíčová slova
mabpac, mabpacmab, mabhplc, hplccolumn, columncolumns, columnsformat, formatsize, sizescfc, scfcmau, mauparticle, particlemin, minmmae, mmaeantibody, antibodycharge, chargevariant
BioLC columns and accessories (Chromatography consumables catalog)
2022|Thermo Fisher Scientific|Brožury a specifikace
Chromatography consumables Connected chromatography solutions Chromatography consumables catalog Comprehensive products to support your chromatography workflows Sample preparation solutions Sample handling solutions Low-flow LC columns and accessories BioLC columns and accessories LC columns and accessories GC columns and accessories • EASY-Spray™…
Klíčová slova
columns, columnsbiolc, biolcmabpac, mabpacaccesories, accesoriessize, sizephase, phasemobile, mobilereading, readingcolumn, columnbuffer, buffervariant, variantpore, porehplc, hplcmab, mablength
2019/2021 Chromatography Consumables Catalog - Bio LC columns and accessories
2019|Thermo Fisher Scientific|Ostatní
Connected chromatography solutions 2019/2021 Chromatography Consumables Catalog The collective power of chromatography Expect reproducible results with sample prep, columns and vials Maximizing your chromatography productivity and achieving reproducible results requires optimizing the whole workflow from sample to knowledge. By choosing…
Klíčová slova
columns, columnsmabpac, mabpacsize, sizelength, lengthcolumn, columnparticle, particlebiolc, biolcproswift, proswiftprotein, proteinvariants, variantspropac, propacexchange, exchangeresolution, resolutionaccessories, accessoriesbiobasic
