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Accurate and reliable quantitation of p-toluenesulfonates genotoxic impurities in an active pharmaceutical ingredient by HPLC-UV

 

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APPLICATION BRIEF 73116 Accurate and reliable quantitation of p-toluenesulfonates genotoxic impurities in an active pharmaceutical ingredient by HPLC-UV Authors Sylvia Grosse, Mauro De Pra, Frank Steiner Thermo Fisher Scientific, Germering, Germany Keywords Genotoxic impurities, p-toluenesulfonates, active pharmaceutical ingredient, aprepitant, UV…
Klíčová slova
tsf, tsftoluenesulfonate, toluenesulfonategenotoxic, genotoxicpropyl, propylmau, mauscientific, scientificaprepitant, aprepitantvanquish, vanquishfisher, fisherisopropyl, isopropylmethyl, methylthermo, thermomin, minethyl, ethylimpurities
APPLICATION NOTE 72976 Identity confirmation and accurate quantitation of a genotoxic impurity in an active pharmaceutical ingredient by UHPLC-UV coupled to a single quadrupole mass detector Authors Sylvia Grosse, Mauro De Pra, Frank Steiner Thermo Fisher Scientific, Germering, Germany Application…
Klíčová slova
aprepitant, aprepitanttsf, tsfimpurity, impuritymethyl, methyltoluenesulfonate, toluenesulfonategenotoxic, genotoxicimpurities, impuritiescounts, countsvanquish, vanquishscientific, scientificthermo, thermominutes, minutestemp, tempsource, sourcettc
APPLICATION NOTE 72976 Identity confirmation and accurate quantitation of a genotoxic impurity in an active pharmaceutical ingredient by UHPLC-UV coupled to a single quadrupole mass detector Authors Sylvia Grosse, Mauro De Pra, Frank Steiner Thermo Fisher Scientific, Germering, Germany Application…
Klíčová slova
aprepitant, aprepitanttsf, tsfimpurity, impuritymethyl, methyltoluenesulfonate, toluenesulfonategenotoxic, genotoxicimpurities, impuritiescounts, countsvanquish, vanquishminutes, minutesscientific, scientificthermo, thermotemp, tempsource, sourcettc
Coupling Mass Detection with UV to Improve Method Sensitivity for Esters of Benzenesulfonic Acid in Analysis of Genotoxic Impurities Margaret Maziarz and Mark Wrona Waters Corporation, Milford, MA, USA A P P L I C AT I O N B…
Klíčová slova
benzenesulfonate, benzenesulfonatebenzenesulfonic, benzenesulfonicibs, ibsebs, ebsgenotoxic, genotoxicesters, estersmbs, mbsimpurities, impuritiesamlodipine, amlodipineintensity, intensityisopropyl, isopropylcoupling, couplingacid, aciddetection, detectionmethyl
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