Prague Meeting on Historical Perspectives of Mass Spectrometry and opening of the Czech Mass Spectrometry Museum

13 - 14. říjen 2021
Konference u příležitosti slavnostního otevření Českého muzea pro hmotnostní spektrometrii bude zaměřena na historii, aktuální stav a perspektivy hmotnostní spektrometrie a přispěje tak k oslavám 70. výročí hmotnostní spektrometrie v našem regionu.
ÚOCHB/IOCB PRAGUE: Prague Meeting on Historical Perspectives of Mass Spectrometry

ÚOCHB/IOCB PRAGUE: Prague Meeting on Historical Perspectives of Mass Spectrometry

The origins of mass spectrometry in Czechia date back to the 1950s when a group of young scientists in the newly founded Czechoslovak Academy of Sciences started to build the first mass spectrometer in the country. Over the years, mass spectrometry gradually developed and gained in importance. The conference will explore the history, status and perspectives of mass spectrometry. It will mark the opening of the Czech Mass Spectrometry Museum and contribute to celebrations of 70th anniversary of mass spectrometry in our region.

Dear colleagues and guests,

On behalf of the organizing committee and organizing institutions, it is a great pleasure to welcome you to the Prague meeting on historical perspectives of mass spectrometry. The conference is held on the inauguration of the Czech Mass Spectrometry Museum and celebrates the 70th anniversary of mass spectrometry in our country.

The origins of mass spectrometry in the Czech Republic date back to the 1950s when the first mass spectrometer was built. Despite the post-war shortage and considerable international isolation of socialist Czechoslovakia, the device was successfully completed and used in the newly founded Czechoslovak Academy of Sciences. Later, commercial instruments started to appear. Mass spectrometry became increasingly important and the community started to grow. Since 1985, summer courses "School of Mass Spectrometry" have been organized regularly. The number of participants in this popular annual one-week event is now over two hundred. National scientific conferences on mass spectrometry have been organized biennially since 2011. Mass spectrometry has become a very important and widely used technique for research and industry.

The Czech Mass Spectrometry Museum has been established at the Institute of Organic Chemistry and Biochemistry of the CAS in Prague. The museum aims to collect and display artifacts related to mass spectrometry, especially those associated with the local geographical region. The technical museum mostly shows the key components of mass spectrometers used in the past and in contemporary laboratory practice. It also collects and displays historical documents, photographs, books, etc. The museum's mission is expressed in two words: education and inspiration. It demonstrates technologies hidden behind the cover and inside the vacuum systems, thus allowing a better understanding of how the mass spectrometers actually work. Displayed technical solutions, prototypes, ideas, and stories can be inspiring for students, scientists, as well as instrument designers.

The Prague Meeting on Historical Perspectives of Mass Spectrometry is a two-day conference devoted to history, status and future perspectives of mass spectrometry. The event will bring an exciting program combining presentations from honorable Czech and international scientists, representatives of producing companies mapping the historical development of their instruments, and young colleagues early in their careers. The early evening poster session will be conveniently followed by a social evening with dinner. The organizing committee will make any possible effort to make sure that your participation will be a scientifically rewarding and pleasurable experience.

Josef Cvačka

Chair of the PMHPMS, Mass Spectrometry Research-Service Group, Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic

Organizing institutions

ÚOCHB/IOCB PRAGUE

Czech Society for Mass Spectrometry/Česká společnost pro hmotnostní spektrometrii

Ioannes Marcus Marci Spectroscopic Society/Spektroskopická společnost Jana Marka Marci

ÚOCHB/IOCB PRAGUE - Czech Society for Mass Spectrometry/Česká společnost pro hmotnostní spektrometrii - Ioannes Marcus Marci Spectroscopic Society/Spektroskopická společnost Jana Marka Marci

Conference program

13th October 2021 (Wednesday)

7:30 - 8:20 REGISTRATION
8:20 - 8:40 OPENING OF THE CONFERENCE

SESSION I (in NLT)

(Chair: František Tureček (University of Washington, United States))

8:40 - 9:30 Computational and Gas-phase Studies in Service of Catalysis Research: Identification of the "Aristocratic Atoms"
  • Helmut Schwarz (Technische Universität Berlin, Germany)
9:30 - 10:00 Mass Spectrometry at the J. Heyrovský Institute of Physical Chemistry
  • Miroslav Polášek (Heyrovský Institute of Physical Chemistry of the CAS, Czech Republic)
10:00 - 10:30 Gas Phase Ion-molecule Reactions in Czechia over 60 Years
  • Patrik Španěl (Heyrovský Institute of Physical Chemistry of the CAS, Czech Republic)
COFFEE BREAK

SESSION II (in NLT)

(Chair: Michal Holčapek (University of Pardubice, Czech Republic))

11:00 - 11:30 Past, Present and Future of Orbitrap Mass Spectrometry (virtual presentation)
  • Alexander Makarov (Thermo Fisher Scientific, Germany)
11:30 - 12:00 Development of Novel Ion-less Matrices for Profiling and Imaging Mass Spectrometry
  • Aleš Svatoš (Max Planck Institute for Chemical Ecology, Germany)
12:00 - 12:30 Mass Spectrometry at the Institute of Organic Chemistry and Biochemistry & Museum Opening
  • Josef Cvačka (Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic)
LUNCH BREAK

SESSION III (in NLT)

(Chair: Miroslav Polášek (Heyrovský Inst. of Physical Chemistry of the CAS, Czech Republic))

14:00 - 14:50 High-resolution Native Mass Spectrometry
  • Albert J. R. Heck (Utrecht University, The Netherlands)
14:50 - 15:20 Noncanonical Ionized DNA Nucleobases and Nucleosides. A Dark Matter of DNA Ionization?
  • František Tureček (University of Washington, United States)
15:20 - 15:50 Mass Spectrometry at the University of Pardubice: Focus on Lipidomics
  • Michal Holčapek (University of Pardubice, Czech Republic)
15:50 - 16:20 Forty Year Evolution of High Throughput Mass Spectrometry: A Perspective (virtual presentation)
  • Tom Covey (SCIEX, Canada)
BREAK

POSTER SESSION & DINNER (in OWTP)

17:30 - 19:00 POSTER SESSION
19:00 - 23:00 SOCIAL EVENT - Conference dinner, concert performance, guided underground tours

14th October 2021 (Thursday)

SESSION IV (in NLT)

(Chair: Jan Preisler (Masaryk University, Czech Republic))

8:40 - 9:30 FT ICR Mass Spectrometry. Is There Room for Further Improvements? (virtual presentation)
  • Evgeny Nikolaev (Skolkovo Institute of Science and Technology, Russia)
9:30 - 10:00 Mass Spectrometry: from Metabolites to Art
  • Karel Lemr (Palacký University Olomouc, Czech Republic)
10:00 - 10:30 Historical Perspectives on Bruker’s Involvement in Mass Spectrometry and the Development of Modern Q-TOF Mass Spectrometry
  • Gary H. Kruppa (Bruker, Czech Republic)
COFFEE BREAK

SESSION V – YOUNG SCIENTISTS (in NLT)

(Chair: Karel Lemr (Palacký University Olomouc, Czech Republic))

11:00 - 11:15 Identification of Novel Fatty Acids in Vernix Caseosa using UV Photodissociation Mass Spectrometry in Combination with Fixed-charge Photo-labile Derivatives
  • Lukáš Cudlman (Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic)
11:15 - 11:30 Mass Spectrometry-based Chemical Proteomics in Protein Post-translational Modifications Analysis
  • Pavel Kielkowski (Ludwig-Maximilians-Universität München, Germany)
11:30 - 11:45 Mapping of Regional and Subregional Unbound Drug Transport Across Blood-Brain Barrier Enabled by Quantitative Mass Spectrometry Imaging
  • Dominika Luptáková (Uppsala University, Sweden)
11:45 - 12:00 Visualization of Polyamines and Amino Acids Alterations in Neonatal Brain Hypoxic-Ischemic Injury in Rats by Mass Spectrometry Imaging
  • Hynek Mácha (Institute of Microbiology of the CAS, Czech Republic)
12:00 - 12:15 Temperature-Controlled Electrospray: A Window into Solution Thermochemistry of Non-Canonical Nucleic Acid Complexes
  • Adam Pruška (ETH Zurich, Switzerland)
12:15 - 12:30 Freeing Aspergillus fumigatus of Polymycovirus Infection renders it More Resistant to Competition with Pseudomonas aeruginosa due to Altered Iron-acquiring Tactics
  • Rutuja Patil (Institute of Microbiology of the CAS, Czech Republic)
LUNCH BREAK

SESSION VI (in NLT)

(Chair: Aleš Svatoš (Max Planck Institute for Chemical Ecology, Germany))

14:00 - 14:50 Native Ambient Mass Spectrometry: Mass Spectrometry Imaging of Intact Proteins and Protein Complexes (virtual presentation)
  • Helen J. Cooper (University of Birmingham, United Kingdom)
14:50 - 15:20 A (Time of) Flight from Ames to Brno: Laser Desorption Mass Spectrometry at Masaryk University
  • Jan Preisler (Masaryk University, Czech Republic)
15:20 - 15:50 The History of Time-of-Flight Mass Spectrometry at: VG - Micromass - Waters (virtual presentation)
  • Mike Morris (Waters Corporation, Manchester, United Kingdom)
15:50 - 16:20 Mass Spectrometry Innovation at Agilent Technologies (virtual presentation)
  • George Stafford (Agilent Technologies, United States)
16:20 - 16:30 CONFERENCE CLOSING

IOCB ChemBioDrug Workshop (in NLT)

(Chair: Josef Cvačka (IOCB, Czech Republic))

17:00 - 17:05 OPENING
17:05 - 17:25 Orbitrap Fusion Lumos: A Versatile Mass Spectrometer for Biomolecules
  • Martin Hubálek (Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic)
17:25 - 17:45 Protein Structure and Interactions Studied by Cross-Linking Mass Spectrometry
  • Petra Junková (Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic)
17:45 - 18:05 Protein Structure and Interactions Studied by Hydrogen Deuterium Exchange Mass Spectrometry
  • Jakub Sýs (Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic)
18:05 - 18:30 HPLC/ESI-MS2 – Based Lipidomic Analysis and MALDI Imaging of Lipids
  • Vladimír Vrkoslav, Štěpán Strnad (Institute of Organic Chemistry and Biochemistry of the CAS, Czech Republic)
18:30 - 19:00 Discussion / User Meeting
WORKSHOP CLOSING

Available also as pdf on Prague Meeting on Historical Perspectives of Mass Spectrometry website

Confirmed Speakers

Venue

The conference will take place in three localities in Prague districts Dejvice and Bubeneč: National Library of Technology (lectures), Institute of Organic Chemistry and Biochemistry of the CAS (vernissage tours), and Old Wastewater Treatment Plant (poster session & dinner).

ÚOCHB/IOCB PRAGUE: Prague Meeting on Historical Perspectives of Mass Spectrometry

Czech Museum of Mass Spectrometry

The museum aims to collect and display artifacts related to mass spectrometry, especially those associated with our geographical region. The technical museum shows key components of mass spectrometers used in the past and in contemporary laboratory practice, and it also displays historical documents, photographs, books, etc. The museum's mission is expressed in two words: education and inspiration. It demonstrates technologies hidden behind the cover and inside the vacuum systems, thus allowing a better understanding how the mass spectrometers actually work. Displayed technical solutions, prototypes, ideas, and stories can be inspiring for students, scientists, and designers of instruments.

ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry

Exhibition

ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry

Website

The website will store the museum database with a detailed description of exhibits and bring topics from MS history.

ÚOCHB/IOCB PRAGUE: Czech Museum of Mass Spectrometry

Donations

The Czech Museum of Mass Spectrometry welcomes donations to its collection: instruments or their parts (broken, damaged, unused), and documents, photographs or books related to MS history.

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