Development of MRM Methods for Monoclonal Antibodies Using Skyline
Aplikace | 2016 | ShimadzuInstrumentace
LC/MS, LC/MS/MS, LC/QQQ
ZaměřeníKlinická analýza
VýrobceShimadzu
Klíčová slovaretension, skyline, cdr, peptide, area, mrm, chain, cdrs, antibodies, peak, development, sequence, trypsin, time, predict, mentioned, tryptic, method, fdpvnvntr, ftywgqgtlvtvsaak, containing, article, monoclonal, antibody, specific, fragments, digestion, heavy, methods, region, used, treatment, amyloid, lba, news, sera, fasta, limitation, acquired, light, conserved, software, antigen, decade, sensitive, differentiated, quantitation, predominantly, using, patient
Podobná PDF
Shimadzu Solutions for Biopharmaceutical - Application Notebook
2018|Shimadzu|Příručky
C10G-E054 Solutions for Biopharmaceutical Application Notebook First Edition: December, 2017 © Shimadzu Corporation, 2017 Solutions for Biopharmaceutical Index Application Notebook Bioanalysis LCMS Bioanalysis of Antibody Drugs Using Fab-Selective Proteolysis nSMOL - Trastuzumab analysis nSMOL, which enables selective proteolysis of the…
Klíčová slova
acid, acidamino, aminoantibody, antibodyglycan, glycannsmol, nsmolerexim, ereximstructure, structurenews, newsaggregates, aggregatesanalysis, analysisnucleic, nucleicmrm, mrmglycans, glycanssizer, sizeraggregate
LCMS Bioanalysis of Antibody Drugs Using Fab-selective Proteolysis “nSMOL Method” — Selection of Signature Peptide —
2017|Shimadzu|Aplikace
C146-E340 LCMS Bioanalysis of Antibody Drugs Using Fab-selective Proteolysis “nSMOL Method” Technical Report — Selection of Signature Peptide — Noriko Iwamoto1, Takashi Shimada1 A b s tra c t: nSMOL (nano-surface and molecular-orientation limited proteolysis) is Shimadzu's completely new, proprietary,…
Klíčová slova
ctx, ctxbrx, brxifx, ifxrtx, rtxnsmol, nsmolfab, fabsignature, signatureifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstysls, ifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslspellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkp, pellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpppsrdeltknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflysklt, ppsrdeltknqvsltclvkgfypsdiavewesngqpennykttppvldsdgsfflyskltreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytl, reeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlvdksrwqqgnvfscsvmhealhnhytqkslslspgk, vdksrwqqgnvfscsvmhealhnhytqkslslspgkantibody, antibodyimmunoglobulin, immunoglobulintrypsin
Analytical Solutions from Cell Culture to Biologics Development and Quality Control
2022|Shimadzu|Postery
Analytical Solutions from Cell Culture to Biologics Development and Quality Control Mridul Mandal; Brian Domanski1; Stephen Kurzyniec1; Stephen Swartz1 1Shimadzu Scientific Instruments, Columbia, MD Overview • • • Biopharmaceuticals such as monoclonal antibodies (mAbs) and antibody drug conjugates (ADCs) have…
Klíčová slova
culture, culturecell, cellundifferentiated, undifferentiatedmabs, mabscharacterization, characterizationantibodies, antibodiescharacterize, characterizemab, mabmonoclonal, monoclonalantibody, antibodywetted, wettedbiologics, biologicsinert, inertproperties, propertiespeptide
Peptide mapping of challenging monoclonal antibodies
2020|Thermo Fisher Scientific|Aplikace
CUSTOMER APPLICATION NOTE 73826 Peptide mapping of challenging monoclonal antibodies Authors: Dan Bach Kristensen1, Trine Meiborg Sloth1, Martin Ørgaard1, Krisztina Radi2 Symphogen, Ballerup, Denmark Thermo Fisher Scientific, Hemel Hempstead, UK 1 2 Keywords: Peptide mapping, monoclonal antibody, mAb, post-translational modifications,…
Klíčová slova
pepsin, pepsintrypsin, trypsinpeptides, peptidesdigest, digestsmart, smartpeptide, peptidelane, lanemapping, mappinghydrophobic, hydrophobicdigestion, digestionisolation, isolationcdr, cdrmicroscans, microscansregions, regionschallenging