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Taking Advantage of Enhanced Sensitivity of the SYNAPT XS HDMS System for the Characterization of Intact Trastuzumab

 

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Application Note mAb Subunit Analysis Using the SYNAPT XS High Resolution Mass Spectrometer Henry Shion, Scott J. Berger, Ying Qing Yu Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract The SYNAPT XS…
Klíčová slova
synapt, synaptbayesspray, bayesspraymass, massdeconvolution, deconvolutionresolution, resolutionmonoisotopic, monoisotopicversatile, versatileresolved, resolvedsubunit, subunitspectrometer, spectrometeradvanced, advancedenhanced, enhancedroutine, routinealgorithm, algorithmrelative
[ TECHNOLOGY BRIEF ] Metabolic Profiling of Urine Samples with the SYNAPT XS High Definition (HDMS) Sarah Lennon, Adam King, and Lee A. Gethings, Waters Corporation, Wilmslow, UK Robert S. Plumb, Waters Corporation, Milford, MA, USA The SYNAPT XS HDMS…
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synapt, synapthdms, hdmslfa, lfaresolution, resolutionstepwave, stepwavephenylanine, phenylaninemetoachlor, metoachlorionization, ionizationmetabolic, metabolicmcpb, mcpbmecoprop, mecoproptransmission, transmissionbrief, briefmcpa, mcpaimproved
ApplicAtion SolutionS for BiophArmAceuticAlS A Focus on Protein Therapeutics Introduction: Key Challenges in Biopharmaceutical Characterization .............................................................................................5 7 PROTEIN mass aNalysIs comprehensive and routine characterization of proteins and peptides by lc/mS and lc/mS e ...............................................................9 characterization of an igG1 monoclonal Antibody…
Klíčová slova
uplc, uplcpeptide, peptideprotein, proteinwaters, watersacquity, acquityglycan, glycanantibody, antibodymass, massglycans, glycanspeptides, peptidessystem, systemanalysis, analysismapping, mappingintact, intactmonoclonal
ApplicAtion SolutionS for BiophArmAceuticAlS A Focus on Protein Therapeutics Introduction: Key Challenges in Biopharmaceutical Characterization .............................................................................................5 7 PROTEIN mass aNalysIs comprehensive and routine characterization of proteins and peptides by lc/mS and lc/mS e ...............................................................9 characterization of an igG1 monoclonal Antibody…
Klíčová slova
uplc, uplcpeptide, peptideprotein, proteinwaters, watersacquity, acquityglycan, glycanantibody, antibodymass, massglycans, glycanspeptides, peptidessystem, systemanalysis, analysismapping, mappingintact, intactmonoclonal
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