LCMS
Další informace
WebinářeO násKontaktujte násPodmínky užití
LabRulez s.r.o. Všechna práva vyhrazena. Obsah dostupný pod licencí CC BY-SA 4.0 Uveďte původ-Zachovejte licenci.
 

Podobná PDF

Toggle
Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos Tribrid Mass Spectrometer
Poster Note 64778 Top-down Characterization of Monoclonal Antibody on an Orbitrap Fusion Lumos™ Tribrid Mass Spectrometer Seema Sharma, Stephane Houel, Christopher Mullen, Chad Weisbrod, Romain Huguet, John Syka, Dave Horn, Jonathan Josephs, Jae Schwartz, Vlad Zabrouskov Thermo Fisher Scientific, San…
Klíčová slova
abundance, abundancefragmentation, fragmentationantibody, antibodyintact, intactetd, etdrelative, relativemab, mabtop, topdown, downheavy, heavymonoclonal, monoclonaldeglycosylated, deglycosylateduvpd, uvpdpulses, pulsessequence
A Complete Workflow Solution for Intact Monoclonal Antibody Characterization Using a New High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS
A Complete Workflow Solution for Intact Monoclonal Antibody Characterization Using a New High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS Zhiqi Hao,1 Yi Zhang,1 David Horn,1 Seema Sharma,1 Shiaw-Lin Wu, 2 Irene Ae-Ning Lin, 3 Yi-Hsuan Pan, 3 Ya-Fen Yang, 3 and Andreas F.…
Klíčová slova
mab, mababundance, abundanceintact, intactrelative, relativeexactive, exactivehcd, hcdspectrum, spectrumfile, fileorbitrap, orbitrapenvelope, envelopemass, massdeconvolution, deconvolutioncharge, chargedown, downantibody
Characterization of Monoclonal Antibodies Oxidation Variants Using Middle-down Approach and Hydrogen/Deuterium Exchange Mass Spectrometry
There is a growing trend to obtain intact mass information as well as the glycan profile in the QC of mAbs using high resolution mass spectrometers. The most commonly employed LC/MS method is to desalt mAbs via reverse phase liquid…
Klíčová slova
trastuzumab, trastuzumabscfc, scfcoxidized, oxidizedmab, mabfigure, figureides, idesdeuterium, deuteriumfragments, fragmentsmabpac, mabpacoxidation, oxidationtic, ticfab, fabdtt, dttpapain, papainerml
Real-Time Instrument Control of the Orbitrap Tribrid Mass Spectrometer
Figu Figure 1. Compatible Mass Spectrometers Orbitrap Fusion Lumos Orbitrap Fusion The IAPI is compatible with both the Thermo Scientific™ Orbitrap™ Fusion™ mass spectrometer and the Thermo Scientific™ Orbitrap™ Fusion Lumos™ mass spectrometer Figure 2. IAPI Architecture • The architecture…
Klíčová slova
iapi, iapifusion, fusionscan, scanrepeating, repeatingcustom, customabundance, abundanceorbitrap, orbitrapscans, scansrelative, relativetribrid, tribridraw, rawmethod, methodtune, tuneimassintensity, imassintensitytime
Další projekty
GCMS
ICPMS
Sledujte nás
Další informace
WebinářeO násKontaktujte násPodmínky užití
LabRulez s.r.o. Všechna práva vyhrazena. Obsah dostupný pod licencí CC BY-SA 4.0 Uveďte původ-Zachovejte licenci.