Effective Strategies for Improved Outcomes in LC Purification

Join us for this two-part webinar series where we will share successful techniques to effectively improve lab-scale HPLC purification to isolate and purify important target compounds.

There is a continuous demand for sufficient yields of high-purity compounds in research and development. Whether compounds are synthesized target molecules, isolated natural product bioactives, or an unknown impurity from an API synthesis, target compound diversity brings new challenges for LC purification. This requires scientists to have a greater understanding of how-to better leverage HPLC for achieving purification outcomes in lab-scale target clean up. With purity requirements and accelerated project timelines, understanding best approaches for preparative separations is valuable to meeting these objectives. We will discuss practical techniques and tools for improving your effectiveness in lab-scale HPLC purifications.

Additionally, we will explore successful approaches to achieving purity and yields at first try, and ways to be more efficient and confident in isolating and purifying important target compounds.

Key Learnings from this series include:

• Gain insights for applying simple techniques to improve lab-scale purifications

• Learn to scale your analytical – prep workflows predictably

• For problematic targets, gain confidence choosing successful strategies to meet purification goals

• Boost preparative workflow efficiency using Waters OBD columns

Who Should Attend?

• Scientists performing mg scale isolation and purification workflows

• Medicinal and Synthetic Chemists in Pharmaceutical & Academia

• Scientists, novices to experts, using HPLC for lab-scale purification of target molecules

Presenter: Kathy Lawrence (Sr. Product Marketing Manager, Waters Corporation)

Kathy Lawrence is the Sr. Product Marketing Manager for prep column technologies at Waters Corporation. Early in her career, she was a discovery R&D chemist and a CRO lab manager gaining valuable experience isolating natural products and synthesizing small molecule targets. Later, as Waters North America Purification Specialist, she travelled the continent supporting the success of others purifying targets at various scale. Kathy has held advanced leadership roles in marketing and business development in support of the commercialization of systems, services, and consumables. She holds a Masters degrees in both chemistry and business, is an author of some scientific publication, and is a patented product inventor.